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- mor-suppressive microRNA (miRNA) molecules called miR-34a and miR-34b/c. Aspirin achieves this by activating the enzyme AMPK, which alters the transcription factor NRF2's activity to increase miR-34 gene expression. Furthermore, aspirin also sup... that would otherwise inhibit NRF2, leading to the miR-34 genes being crucial for aspirin's inhibitory e
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- -376dc112c040|Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer met